山梨医科大学雑誌　第13巻1号　009-013(1998)

Comparison of Pregnancy Rates between Fallopian Tube Sperm
Perfusion and Standard Intrauterine Insemination

Tsuyoshi KASAI, Seiichiro NAGAI, Kaoruko MIZUNO, Keigo OGAWA, Shouji OHTA, and Kazuhiko HOSHI

Abstract: This study retrospectively compared the clinical pregnancy rate (PR) per cycle using Fallopian tube sperm perfusion (FSP) to that obtained by intrauterine insemination (IUI) in relation to the number of motile sperm inseminated. We studied 76 infertile women aged 25 to 38 years who had undergone 216 insemination cycles with sperm prepared by the Percoll method between July 1994 and June 1995. Infertility was either unexplained or due to male infertility. All women in this study demonstrated tubal patency and spontaneous ovulatory cycles. Insemination was performed during an unstimulated cycle. Each cycle was scheduled for either FSP(N=52) or IUI(N=164) treatment. FSP was performed using a tubal patency test catheter with 4 ml of sperm suspension. IUI was performed with 0.5 ml of the suspension. Our results did not show any significant difference in the PR between the two groups. These results indicated that the FSP techniqu did not improve the PR, as compared to that achieved with standard IUI. However, a tendency toward a higher PR in the FSP group wa obained. It is well worth trying before moving on to more invasive and costly approached, such as gamete intrafallopian transfer (GIFT) or in vitro fertilization and embryo transfer (IVF-ET).

Key words: Intrauterine insemination, Fallopian tube sperm perfusion




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