山梨医科学雑誌　第18巻1号　015-020(2003)

＜Original Article＞
Parafoveal Scanning Laser Polarimetry for
Early Glaucoma Detection

Satoshi KOGURE, Yoshiki TODA, Hiroyuki IIJIMA and Shigeo TSUKAHARA

Abstract: Purpose: To investigate the glaucoma change detection in the parafoveal area using scanning laser polarimeter (SLP).
Methods: Fourteen eyes with early glaucoma which have a point with 6 dB or more decrease in pattern deviation with the Humphrey Field Analyzer (HFA) 30-2 program within central 10 degrees visual field, and 14 normal control eyes were enrolled in this study. The average of the mean deviation with the HFA was -3.74±2.72dB (ranged from +0.53dB to -7.45dB), and the average of the corrected pattern standard deviation with the HFA was 5.17±3.07dB (ranged from 0.55dB to 10.43 dB) in glaucoma eyes. The fundus images centered on the fovea were taken three times using SLP for each eye. In each fundus image, the nerve fiber layer thickness was measured along a circle of 5.3 degree in diameter around the fovea. The circle was divided into 12 sectors on each 30 degrees area. The ratios between areas across the fovea were calculated from the 12 sectors for six pairs. The values of these ratios were compared between glaucoma eyes and normal controls.
Results: The glaucoma eyes had smaller ratios (p = 0.0004, Student-t test). This means that there is a thinning of superior retinal nerve fiber layer thickness.
Conclusions: Scanning laser polarimetry has potential to detect the glaucoma change not only around optic disc but also in the macular area.

Key words: glaucoma, nerve fiber layer thickness, fovea, scanning laser polarimetry




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