山梨医科大学雑誌　第4巻3号　125-132(1989)

Quantitative Analysis of Deformed Liver of Schistosomiasis
Japonica and its Possible Causative Factors

Shingo INOEUE, Masayuki YAMAMOTO, Yuji IIMURO, Hidehisa AOYAMA,
Yoshiro MATSUMOTO, and Katsuhiko SUGAHARA

Abstract: Carrier rate of calcified ova of Schistosomiasis japonica (Sj) was 19.6% among cases at Yamanashi Medical College, Japan. In 45 Sj cases who underwent preoperative CT, possible causative factors inducing deformed Sj livers, such as the numbers of calcified ova, extent of calcification or volume of the spleen, were analyzed with regard to the degree of deformity, and ratio of the right lobe to the left and caudate lobes. A relationship between the degree of deformity and liver function was also studied. Among the 45 cases, 41 cases had liver fibrosis and 4 were accompanied by liver cirrhosis. A negative correlation between the total liver volume and age was observed, but mean total liver volumes were not significantly different from control cases. The degree of deformity of the Sj livers was diverse and showed no significant relation with the spleen volume or the numbers of calcified ova counted microscopically. In Sj cases, the greater the degree of calcification observed via CT images, the more the right lobe tended towards atrophy and the left and caudate lobes towards enlargement. Liver function in the Sj cases was little impaired unless cirrhotic changes occurred, even though the deformity was severe.

Key words: Schistosomiasis japonica, Deformity of the liver, Liver-function, Hypersplenism, Calcification of the liver




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