山梨医科大学雑誌　第5巻3号　147-150(1990)

Effects of Six Beta Blocking Agents on Cardiovascular Responses
during Exercise

Atsushi SUGIYAMA, Takeo AwWJI, Nobuo HOMMA, Kohji TAMURA, and Keitaro HASHIMOTO

Abstract: The cardiovascular effects of six beta blocking agents; atenolol (50 mg), carteolol (5 mg), propranolol (10 mg), nipradilol (3 mg), dilevalol (100 mg) and metoprolol (40 mg) during Master's test exercise were assessed in 85 healthy young adults. All drugs significantly reduced the increments in pressure-rate product during exercise at 1 hr as well as 2 hr after the drug administration, which might reflect myocardial oxygen consumption. Therefore, after administration of these beta blockers, an equivalent workload can be achieved with less myocardial oxygen consumption. The potency of 6 drugs at 1 hr after drug administration was: metoprolol>nipradilol>atenolol>propranolol>dilevalol>carteolol, and that at 2 hr after administration was: atenolol>carteolol>metoprolol>propranolol>dilevalol>nipradilol.

Key words: Beta blockers, Master's Test, Nipradilol, Dilevalol, Healthy Young Adults




本文は、編集委員会の意向によりインターネットには公開しておりません。図書館等でご覧ください。

Texts are not availavle on Internet.



目次・Contentsに戻る