山梨肺癌研究会会誌　第11巻2号　088-095(1998)

気管支肺胞洗浄液のCD4/CD8分割比の低下を契機に診断に至ったAIDSに合併したカリニ肺炎の１例

山本夏男，安田公彦，宮下義啓，千葉直彦，小泉史明，長田忠孝，三俣昌子

Key words：過敏性肺臓炎，ground glass opacity，カリニ肺炎，AIDS，CD4/8比



A case of Pneumocystis Carinii Pnuemonia in an AIDS patient Diagnosed by decreased CD4/CD8 ratio of Bronchoalveolar lavage Fluid

Natsuo Yamamoto, Kimihiko Yasuda, Yohihiro Miyashita, Naohiko Chiba, Fumiaki Koizumi, Chyukou Osada, Masako Mitsumata

Abstract：This case is 44-year-old man who was admitted with recurrent fever, non-productive cough, and dyspnes. Chest X-ray and CT showed bilateral diffuse ground glass opacity with peripheral clear zone. Hypersensitivity pneumonitis, Bronchiolitis obliterans organizing pneumonia (BOOP), Drug-induced pneumonia were considered as differential diagnoses. Cellular analysis of Bronchoalveolar Lavage Fluid (BALF) reveald CD4/CD8(T-cell) ratio markedly decreased:0.03. Pnuemocystis carinii pneumonia was diagnosed by Transbronchial lung biopsy (TBLB). A serological test for human immuno-deficiency virus(HIV)-1 was positive. This case and other reports suggests that markedly reduced CD4/CD8(T-cell) ratio in BALF indicates PCP in AIDS patients.



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