山梨医科大学紀要　第12巻，023-034(1995)

Factors Relevant to Ciliary Activity of the Airway Mucosa

Ken-ichi HISAMATSU

　Mucociliary transport is one of the essential defensive functions of the airway mucosa. Dysfunction of this system facilitates recurrent and chronic mucosal inflammation and allergy of the alrway. In this paper, factors relevant to mucociliary function are reviewed with 11O references. The bioactive substances that are reviewed in this paper are as follows: immune complexes, viruses, bacteria, allergen, MBP, elastase, sulfide peptide leukotrienes, platelet activating factor, prostaglandins, histamine, bradykinin, neuropeptides, autonomic neurotransmitters, lysozyme, etc.

key words: ciliary actfvity, inflammatory mediators, neurotransmitter, neuropeptides, bioactive substances



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