山梨医科大学紀要 第13巻，001-006(1996)
手錠をかけられた直後に死亡した覚せい剤中毒の2解剖例
大矢正算，井上利男，竹川健一，木戸 啓，西園敏子，山田 正，三ッ国洋一
覚せい剤を一方が注射し，他方が注射後服用したと思われた中毒死の2解剖例を報告する。
事例1:42歳の男性がホテルで異常に興奮し暴れたため，警察官が保護の目的で手錠をかけたところまもなく死亡した。室内からは白色粉末入りパック2個と注射器1組が発見された。死者の左右肘窩と右下腿前面には瘢痕化した注射痕がみられた。死後28時間して解剖が行われ，直腸温は34℃であった.肺は著明な浮腫とうつ血を示した。心は肥太し，線維化と心筋線維の乱れがみとめられた。GC/MS法およびGC法により血中に5.6，胃内容中に9.7，左注射痕に24.6，右注射痕に11.7μmol/100gのメタンフェタミンが検出された。死者は覚せい剤の常習者であり，過量を注射したため死亡したものと考えられた。
事例2:33歳の男性が路上車外で異常に興奮し暴れたため，警察官が保穫の目的で手錠をかけたところまもなく死亡した。車の下には白色粉末入りパック1個と注射器3本が散乱し，このうち2本には半溶解した粉末と破れたパックがつめこまれていた。死者の右肘窩には出血を伴う注射痕が2カ所にみられた。陰毛はそられていた。解剖の結果，肺に著明な浮腫とうっ血がみとめられたが，心はほぼ正常であった。GC/MS法およびGC法により血中に4.6，胃内容中に298，左注射痕に2.8μmo1/100gのメタンフェタミンが検出された。死者は覚せい剤を注射したが不十分だったため，さらにその粉末を服用したものと考えられた。
キーワード：覚せい剤中毒，薬物乱用，裁判化学，行政解剖，司法解剖
Two Autopsy Cases of Methamphetamine Poisoning in Which the Abusers Died Shortly after Being Handcuffed
Masakazu OYA, Toshio INOUE, Kenichi TAKEKAWA, Akira KIDO, Toshiko NISHIZONO, Tadashi YAMADA, Youichi MITSUKUNI
Two autopsy cases of methamphetamine poisoning are reported in which one seemed to have injected, but the other injected and then ingested.
Case 1 : A 42-year old man struggled in an abnormal state of excitement at a hotel and died shortly after the police handcuffed him for protection. Two packs containing white powder and a syringe were found in the room. On both cubital fossae and the right pretibial region of the deceased scarred needle punctures were seen. Autopsy was performed about 28 hours after death, and the rectal temperature was 34℃. The lungs were severely edematous and congested. The heart was enlarged. Histology revealed cardiac fibrosis and disarrangement of myofibers. By the GC/MS and GC methods the concentrations of methamphetamine(μmo1/100 g) were estimated to be 5.6 in blood, 9.7 in gastric contents, 24.6 in left needle puncture and 11.7 in right needle puncture. The deceased seemed to be a chronic methamphetamine abuser and death was considered to be caused by an overdose injection of methamphetamine.
Case 2 : A 33-year old man struggled in an abnormal state of excitement outside his car on a road and died shortly after the police handcuffed him for protection. A pack containing white powder and three syringes were lying about under the car, two of which were filled with incompletely dissolved powder and a broken pack. On the right cubital fossa of the deceased two needle punctures with hemorrhage were seen. The pubic hairs were shaven. Autopsy showed severe Pulmonary edema and congestion. The myocardium was almost normal. By the GC/MS and GC methods the concentrations of methamphetamine(μmo1/100 g) were estimated to be 4.6 in blood, 298 in gastric contents and 2.8 in left needle puncture. The deceased was considered to have poorly injected methamphatamine and then swallowed the powder.
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